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    Two Sigma Investments, LP

    CIK Number: 0001179392

    56,473.6B
    Market Value
    2,953
    # of Holdings
    9 months
    Avg. Holding Period
    Win Rate
    Peformance 3-Years
    Main Sectors:
    Healthcare Financial Services Technology
    Top Industries:
    Biotechnology Banks - Regional Software - Application

    Filing Date: May 15, 2025

    Rank Symbol Name Price % Change Shares % Change Shares Market Value Avg. Price Paid % Weight Asset Type
    1 SPY SPDR S&P 500 ET...
    644.93
    		+0.01% 1.49M +138.29% 836.14M 520.21 1.79% Share
    2 XLK Technology Sele...
    267.74
    		-0.21% 2.09M +64.92% 431.27M 217.13 0.92% Share
    3 QQQ Invesco QQQ Tru...
    579.86
    		-0.08% 907.64K +22.15% 425.61M 400.63 0.91% Share
    4 VUG Vanguard Growth...
    463.54
    		+0.15% 1.02M +18.12% 378.57M 359.69 0.81% Share
    5 IWF iShares Russell...
    450.40
    		+0.11% 1.04M +8.62% 375.75M 337.52 0.80% Share
    6 IVV iShares Core S&...
    648.15
    		+0.01% 559K -0.2% 314.1M 527.9 0.67% Share
    7 CME CME Group Inc.
    274.71
    		+0.29% 1.02M -1.77% 270.25M 192.86 0.58% Share
    8 AVGO Broadcom Inc.
    311.19
    		+0.68% 1.56M +2.57K% 261.13M 167.24 0.56% Share
    9 CRM Salesforce, Inc...
    233.32
    		-1.57% 965.72K +700.67% 259.16M 275.73 0.55% Share
    10 LMT Lockheed Martin...
    437.38
    		-1.17% 567.94K +17.48% 253.7M 438.6 0.54% Share
    11 NVDA NVIDIA Corporat...
    182.02
    		+0.24% 2.33M +28.11% 252.86M 77.63 0.54% Share
    12 LNG Cheniere Energy...
    232.63
    		+0.58% 1.07M -0.91% 247.78M 185.09 0.53% Share
    13 BSX Boston Scientif...
    104.16
    		+1.62% 2.44M +229.01% 246.22M 92.97 0.53% Share
    14 GOOGL Alphabet Inc.
    202.88
    		+0.46% 1.59M +16.40% 245.76M 163.85 0.53% Share
    15 MRVL Marvell Technol...
    79.03
    		-0.37% 3.93M +316.21% 242.07M 72.22 0.52% Share
    16 SNOW Snowflake Inc.
    194.85
    		-1.02% 1.65M +16.27% 240.92M 151.12 0.51% Share
    17 COR Cencora, Inc.
    294.88
    		+1.32% 858.61K +14.47% 238.77M 199.35 0.51% Share
    18 MSCI MSCI Inc.
    565.92
    		-0.27% 421.65K +64.03% 238.44M 524.31 0.51% Share
    19 PLTR Palantir Techno...
    181.00
    		-1.83% 2.82M +5.01K% 237.73M 83.78 0.51% Share
    20 ADBE Adobe Inc.
    348.58
    		-0.71% 619.54K +36.80% 237.61M 453.29 0.51% Share
    21 REGN Regeneron Pharm...
    565.97
    		+0.79% 372.07K +977.12% 235.98M 661.87 0.50% Share
    22 RBLX Roblox Corporat...
    125.28
    		-1.18% 4M -11.4% 233.15M 47.54 0.50% Share
    23 TSLA Tesla, Inc.
    335.58
    		-1.12% 897.35K +49.74% 232.56M 355.78 0.50% Share
    24 AAPL Apple Inc.
    232.81
    		-0.22% 1.05M -7.41% 232.53M 191.16 0.50% Share
    25 AMD Advanced Micro ...
    180.97
    		-1.87% 2.25M +100.00% 230.85M 102.74 0.49% Share
    26 DASH DoorDash, Inc.
    247.42
    		-2.67% 1.26M -17.29% 230.6M 79.17 0.49% Share
    27 XLV Health Care Sel...
    133.94
    		+0.49% 1.56M -34.24% 227.7M 141.99 0.49% Share
    28 HUM Humana Inc.
    281.43
    		-0.2% 856.78K +45.95% 226.7M 326.99 0.48% Share
    29 DHR Danaher Corpora...
    210.15
    		+0.48% 1.11M +7.60% 226.65M 238.63 0.48% Share
    30 DG Dollar General ...
    114.69
    		-0.95% 2.56M +8.61% 224.83M 78.88 0.48% Share
    31 MSFT Microsoft Corpo...
    522.28
    		+0.33% 594.75K -1% 223.26M 360.06 0.48% Share
    32 MA Mastercard Inco...
    583.65
    		+0.99% 406.42K -4.04% 222.77M 399.16 0.48% Share
    33 IT Gartner, Inc.
    242.94
    		+0.12% 523.26K +484.47% 219.63M 424.13 0.47% Share
    34 MCK McKesson Corpor...
    673.84
    		+1.61% 325.93K +97.85% 219.35M 618.61 0.47% Share
    35 NVO Novo Nordisk A/...
    50.92
    		+0.04% 3.15M +70.67% 218.59M 79.15 0.47% Share
    36 IQV IQVIA Holdings ...
    189.40
    		-0.44% 1.23M +59.69% 216.22M 194.78 0.46% Share
    37 CNC Centene Corpora...
    26.93
    		-0.5% 3.56M +58.38% 215.91M 61.12 0.46% Share
    38 MELI MercadoLibre, I...
    2319.80
    		-0.32% 110.23K +1.49K% 215.04M 1934.28 0.46% Share
    39 ANET Arista Networks...
    136.47
    		-1.12% 2.77M +501.42% 214.39M 82.98 0.46% Share
    40 ICE Intercontinenta...
    182.62
    		+0.67% 1.24M +24.86% 213.73M 151.92 0.46% Share
    41 ISRG Intuitive Surgi...
    477.00
    		-1.11% 411.66K +502.64% 203.88M 499.34 0.44% Share
    42 FTNT Fortinet, Inc.
    77.25
    		-2.62% 2.1M -3.04% 201.96M 59.41 0.43% Share
    43 LIN Linde plc
    477.49
    		+0.39% 429.73K +232.80% 200.1M 452.42 0.43% Share
    44 MRK Merck & Co., In...
    82.74
    		+0.04% 2.2M +14.10% 197.53M 114.34 0.42% Share
    45 NFLX Netflix, Inc.
    1230.56
    		+2.17% 211.24K -24.47% 196.99M 546.2 0.42% Share
    46 WCN Waste Connectio...
    184.77
    		-0.52% 1M +3.12% 195.84M 177.84 0.42% Share
    47 NOC Northrop Grumma...
    583.89
    		+0.31% 374.25K -15.65% 191.62M 454.47 0.41% Share
    48 NOW ServiceNow, Inc...
    850.65
    		-1.42% 238.44K +5.31K% 189.83M 794.95 0.41% Share
    49 SPLG SPDR Portfolio ...
    75.87
    		+0.01% 2.88M -16.26% 189.3M 64.79 0.40% Share
    50 META Meta Platforms,...
    781.96
    		+0.24% 328.39K -19.16% 189.27M 555.91 0.40% Share
    51 COP ConocoPhillips
    95.63
    		-0.26% 1.74M +12.91K% 182.38M 105.11 0.39% Share
    52 VTI Vanguard Total ...
    317.25
    		-0.13% 663.33K -10.83% 182.31M 272.87 0.39% Share
    53 LHX L3Harris Techno...
    270.96
    		+0.27% 861.56K +87.37% 180.33M 210.19 0.39% Share
    54 CMCSA Comcast Corpora...
    32.88
    		-0.17% 4.88M +305.02% 179.96M 38.1 0.38% Share
    55 DHI D.R. Horton, In...
    163.90
    		-1% 1.35M +54.10% 171.93M 135.28 0.37% Share
    56 IYW iShares U.S. Te...
    184.93
    		-0.22% 1.22M +65.07% 171.07M 140.82 0.37% Share
    57 VRSK Verisk Analytic...
    267.70
    		+1.33% 570.53K +39.88% 169.8M 258.88 0.36% Share
    58 OXY Occidental Petr...
    44.77
    		+0.06% 3.43M +359.90% 169.31M 49.61 0.36% Share
    59 TMO Thermo Fisher S...
    485.13
    		+0.07% 331.26K -26.68% 164.84M 544.85 0.35% Share
    60 QCOM QUALCOMM Incorp...
    158.09
    		+0.96% 1.06M -32.57% 162.4M 161.75 0.35% Share
    61 KRE SPDR S&P Region...
    62.61
    		-0.05% 2.78M +106.68% 157.88M 53.13 0.34% Share
    62 NET Cloudflare, Inc...
    195.34
    		-2% 1.38M +325.44% 155.96M 102.1 0.33% Share
    63 MSI Motorola Soluti...
    461.76
    		-1.79% 354.09K +50.84% 155.03M 341.32 0.33% Share
    64 SCHW The Charles Sch...
    97.75
    		+2.26% 1.95M +193.88% 152.35M 74.41 0.33% Share
    65 MLM Martin Marietta...
    612.14
    		-1.28% 315.55K +33.05% 150.87M 514.59 0.32% Share
    66 AMCR Amcor plc
    8.76
    		-11.92% 15.34M +1.5K% 148.81M 9.68 0.32% Share
    67 WM Waste Managemen...
    225.97
    		-1.71% 642.4K +9.19% 148.72M 201.73 0.32% Share
    68 GD General Dynamic...
    315.89
    		-0.5% 538.65K -22.35% 146.82M 284.98 0.31% Share
    69 TWLO Twilio Inc.
    100.79
    		-0.9% 1.45M +28.27% 141.88M 103.44 0.30% Share
    70 KDP Keurig Dr Peppe...
    34.63
    		-0.55% 4.07M +23.03% 139.43M 32.65 0.30% Share
    71 AMZN Amazon.com, Inc...
    230.94
    		+2.84% 727.72K -39.47% 138.46M 218.33 0.30% Share
    72 PANW Palo Alto Netwo...
    173.55
    		-1.87% 807.48K +98.40% 137.79M 176.33 0.29% Share
    73 SE Sea Limited
    174.01
    		-0.37% 1.04M +9.03% 135.61M 88.04 0.29% Share
    74 CAH Cardinal Health...
    150.22
    		+1.42% 984.22K +4.31% 135.6M 103.81 0.29% Share
    75 XLU Utilities Selec...
    85.85
    		-0.72% 1.7M -21.1% 134.34M 75.69 0.29% Share
    76 TEAM Atlassian Corpo...
    164.39
    		+0.24% 630.8K +37.36% 133.86M 189.21 0.29% Share
    77 SPOT Spotify Technol...
    698.73
    		+0.54% 240.99K -31.54% 132.55M 284.6 0.28% Share
    78 AMAT Applied Materia...
    188.22
    		-0.95% 910.18K -32.46% 132.09M 162.51 0.28% Share
    79 HUBS HubSpot, Inc.
    429.41
    		-1.91% 231.03K +61.31% 131.98M 609.39 0.28% Share
    80 EIX Edison Internat...
    56.02
    		-0.45% 2.2M +2.41K% 129.9M 59.65 0.28% Share
    81 ETR Entergy Corpora...
    90.30
    		-0.75% 1.5M +47.15% 128.37M 68.74 0.27% Share
    82 RSG Republic Servic...
    232.53
    		-0.09% 524.69K +21.78% 127.06M 163.36 0.27% Share
    83 EFX Equifax Inc.
    248.02
    		-2.08% 520.58K +310.30% 126.79M 255.52 0.27% Share
    84 MRNA Moderna, Inc.
    26.69
    		-0.74% 4.45M +570.76% 126.27M 34.02 0.27% Share
    85 BAH Booz Allen Hami...
    108.16
    		-3.11% 1.19M +1.86K% 124.01M 107.55 0.27% Share
    86 CVNA Carvana Co.
    342.60
    		-2.08% 587.7K -48.73% 122.88M 27.81 0.26% Share
    87 BIIB Biogen Inc.
    134.95
    		-0.18% 879.33K +3.17% 120.33M 189.83 0.26% Share
    88 CBOE Cboe Global Mar...
    243.58
    		-0.75% 526.9K -3.68% 119.23M 150.6 0.25% Share
    89 ORCL Oracle Corporat...
    244.93
    		+0.31% 852.07K +6.31K% 119.13M 139.23 0.25% Share
    90 EQIX Equinix, Inc.
    774.95
    		-1.15% 145.55K +734.27% 118.67M 830.64 0.25% Share
    91 CSX CSX Corporation
    36.35
    		+0.75% 4.02M +411.60% 118.42M 30.21 0.25% Share
    92 WST West Pharmaceut...
    246.35
    		+0.05% 522.83K +588.04% 117.05M 237.01 0.25% Share
    93 COST Costco Wholesal...
    975.42
    		-0.35% 123.02K -27.16% 116.35M 598.96 0.25% Share
    94 CI The Cigna Group
    290.40
    		+1.15% 353.14K -53.83% 116.18M 329.41 0.25% Share
    95 ADC Agree Realty Co...
    72.20
    		-0.1% 1.5M +61.35% 115.59M 70.03 0.25% Share
    96 VEEV Veeva Systems I...
    275.00
    		-1.5% 498.81K +44.77% 115.54M 213.36 0.25% Share
    97 F Ford Motor Comp...
    11.44
    		-0.04% 11.5M +2.14K% 115.38M 10.08 0.25% Share
    98 MNST Monster Beverag...
    64.18
    		+0.05% 1.96M +163.35% 114.71M 56.25 0.25% Share
    99 AMGN Amgen Inc.
    290.28
    		+0.33% 359.52K -60.16% 112.01M 275.12 0.24% Share
    100 AEP American Electr...
    112.87
    		-0.21% 1.02M +1.67K% 111.73M 108.27 0.24% Share
    101 IBKR Interactive Bro...
    63.91
    		+0.66% 671.85K +37.34% 111.25M 166.43 0.24% Share
    102 SOFI SoFi Technologi...
    23.29
    		-2.18% 9.5M -40.12% 110.5M 14.01 0.24% Share
    103 YUM Yum! Brands, In...
    146.79
    		+1.38% 689.71K +100.00% 108.53M 157.36 0.23% Share
    104 HEI HEICO Corporati...
    311.15
    		-0.57% 406.03K +61.60% 108.49M 212.07 0.23% Share
    105 KBE SPDR S&P Bank E...
    58.83
    		-0.05% 2.01M +5.3K% 106.46M 52.83 0.23% Share
    106 ADSK Autodesk, Inc.
    283.84
    		-1.1% 402.55K +2.78K% 105.39M 261.27 0.23% Share
    107 FNV Franco-Nevada C...
    177.30
    		-1.03% 662.93K -35.6% 104.45M 116.31 0.22% Share
    108 ECL Ecolab Inc.
    279.98
    		-0.66% 406.26K +14.30% 103M 206.97 0.22% Share
    109 QUAL iShares MSCI US...
    188.56
    		-0.07% 601K +3.14% 102.7M 152.17 0.22% Share
    110 HOOD Robinhood Marke...
    110.69
    		+1.91% 2.39M -60.72% 99.53M 15.55 0.21% Share
    111 CNQ Canadian Natura...
    29.78
    		-0.52% 3.21M +28.50% 98.88M 33.65 0.21% Share
    112 SU Suncor Energy I...
    38.98
    		+0.12% 2.55M +47.38% 98.71M 37.05 0.21% Share
    113 IWB iShares Russell...
    354.15
    		-0.03% 321.5K -15.17% 98.62M 301.21 0.21% Share
    114 ENPH Enphase Energy,...
    32.23
    		-5.82% 1.59M +960.33% 98.47M 66.35 0.21% Share
    115 EXE Expand Energy C...
    94.99
    		-1.52% 868.14K +100.00% 96.64M 111.32 0.21% Share
    116 MOS The Mosaic Comp...
    32.08
    		-0.42% 3.57M +38.33% 96.39M 29.77 0.21% Share
    117 BE Bloom Energy Co...
    45.05
    		+2.20% 4.83M +34.30% 95.01M 17.79 0.20% Share
    118 CCL Carnival Corpor...
    30.25
    		-1.27% 4.85M -24.45% 94.67M 13.83 0.20% Put
    119 MKTX MarketAxess Hol...
    187.37
    		-0.86% 430.52K +49.32% 93.14M 212.02 0.20% Share
    120 MGK Vanguard Mega C...
    389.58
    		+0.29% 299K +26.37% 92.36M 311.24 0.20% Share
    121 VGT Vanguard Inform...
    704.44
    		-0.4% 169.5K +23.27% 91.93M 591.22 0.20% Share
    122 VONG Vanguard Russel...
    115.87
    		+0.12% 988.9K +36.85% 91.76M 93.04 0.20% Share
    123 PKG Packaging Corpo...
    196.49
    		-2.14% 463.28K +31.04% 91.74M 210.3 0.20% Share
    124 AAL American Airlin...
    12.82
    		-2.17% 8.65M +313.01% 91.31M 12.19 0.20% Share
    125 XLB Materials Selec...
    90.03
    		-1.04% 1.05M +100.00% 90.03M 85.98 0.19% Share
    126 SCHG Schwab U.S. Lar...
    30.76
    		+0.13% 3.56M +11.02% 89.08M 25.84 0.19% Share
    127 IWY iShares Russell...
    261.68
    		+0.21% 419.7K +41.36% 88.53M 213.98 0.19% Share
    128 XLG Invesco S&P 500...
    55.23
    		+0.35% 1.92M +79.72% 88.13M 46.57 0.19% Share
    129 KR The Kroger Co.
    69.23
    		-1.56% 1.3M +72.77% 88.12M 55.01 0.19% Share
    130 BILL Bill.com Holdin...
    39.46
    		-2.36% 1.9M +72.48% 87.35M 58.77 0.19% Share
    131 MDT Medtronic plc
    91.95
    		-1.03% 963.85K +71.07% 86.61M 88.28 0.19% Share
    132 STM STMicroelectron...
    25.84
    		-1.19% 3.93M -12.22% 86.27M 32.04 0.18% Share
    133 VIK Viking Holdings...
    60.01
    		+0.03% 2.16M -9.31% 85.99M 43.62 0.18% Share
    134 ASML ASML Holding N....
    755.11
    		-0.06% 129.73K +39.57K% 85.96M 663.51 0.18% Share
    135 EAT Brinker Interna...
    157.93
    		+0.35% 572.49K +177.18% 85.33M 118.68 0.18% Share
    136 SYK Stryker Corpora...
    378.47
    		-0.13% 227.63K +67.78% 84.73M 345.79 0.18% Share
    137 ROP Roper Technolog...
    524.96
    		+0.47% 143.19K +100.00% 84.42M 589.58 0.18% Share
    138 PNW Pinnacle West C...
    91.92
    		-1.23% 882.64K -8.21% 84.07M 83.04 0.18% Share
    139 CSCO Cisco Systems, ...
    69.28
    		-1.58% 1.35M -59.68% 83.59M 51.57 0.18% Share
    140 TSM Taiwan Semicond...
    240.97
    		-0.19% 503.15K +64.81% 83.52M 170.65 0.18% Share
    141 ABNB Airbnb, Inc.
    124.71
    		+0.13% 698.65K -57.4% 83.46M 131.41 0.18% Share
    142 SWKS Skyworks Soluti...
    75.36
    		+2.32% 1.29M +521.90% 83.08M 70.64 0.18% Share
    143 INTC Intel Corporati...
    23.86
    		+7.38% 3.63M -69.35% 82.45M 20.05 0.18% Share
    144 UPS United Parcel S...
    88.56
    		+0.43% 734.22K +11.65% 80.76M 138.67 0.17% Share
    145 JNPR Juniper Network...
    39.95
    		+0.05% 2.19M +100.00% 79.24M 36.19 0.17% Share
    146 JBHT J.B. Hunt Trans...
    144.47
    		-0.95% 532.01K +1.07K% 78.71M 150.17 0.17% Share
    147 FMC FMC Corporation
    37.27
    		-0.71% 1.86M +190.29% 78.38M 49.23 0.17% Share
    148 VRNS Varonis Systems...
    56.95
    		-1.98% 1.93M +46.95% 77.88M 44.33 0.17% Share
    149 GH Guardant Health...
    60.36
    		+3.06% 1.83M -3.43% 77.78M 27.62 0.17% Share
    150 EVR Evercore Inc.
    313.54
    		-0.42% 389.37K +158.47% 77.76M 219.38 0.17% Share