Siren, L.l.c.
CIK Number: 0002005245
Main Sectors:
Top Industries:
Filing Date: May 23, 2025
| Rank | Symbol | Name | Price | % Change | Shares | % Change Shares | Market Value | Avg. Price Paid | % Weight | Asset Type |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | SRRK | Scholar Rock Ho... | 32.29 | +0.97% | 9.25M | 0.00% | 297.39M | 8.01 | 16.78% | Share |
| 2 | BGNE | BeiGene, Ltd. | 184.71 | +0.49% | 498.69K | -23.72% | 135.73M | 219.01 | 7.66% | Share |
| 3 | KYMR | Kymera Therapeu... | 41.57 | +2.06% | 3.24M | +9.11% | 88.69M | 45.66 | 5.00% | Share |
| 4 | BPMC | Blueprint Medic... | 129.46 | +0.14% | 726.17K | +100.00% | 64.27M | 88.51 | 3.63% | Share |
| 5 | CRNX | Crinetics Pharm... | 29.69 | -1.33% | 1.69M | +4.91% | 56.64M | 50.28 | 3.19% | Share |
| 6 | APLS | Apellis Pharmac... | 27.62 | +3.91% | 2.58M | -8.45% | 56.39M | 29.55 | 3.18% | Share |
| 7 | IRON | Disc Medicine, ... | 60.75 | -0.57% | 1.07M | +100.00% | 53.21M | 49.64 | 3.00% | Share |
| 8 | SLNO | Soleno Therapeu... | 77.36 | -4.66% | 727.34K | +106.74% | 51.97M | 58.63 | 2.93% | Share |
| 9 | ASND | Ascendis Pharma... | 191.88 | +0.42% | 287.37K | -3.35% | 44.79M | 149.31 | 2.53% | Share |
| 10 | MRUS | Merus N.V. | 66.94 | -0.22% | 1.04M | +33.03% | 43.92M | 47.23 | 2.48% | Share |
| 11 | BCAX | Bicara Therapeu... | 11.43 | +0.88% | 3.27M | -0.18% | 42.57M | 24.98 | 2.40% | Share |
| 12 | CNTA | Centessa Pharma... | 17.63 | +2.83% | 2.96M | -1.49% | 42.57M | 15.99 | 2.40% | Share |
| 13 | NAMS | NewAmsterdam Ph... | 25.17 | -2.29% | 1.91M | -8.76% | 39.14M | 21.7 | 2.21% | Share |
| 14 | EWTX | Edgewise Therap... | 13.92 | +1.38% | 1.7M | +131.02% | 37.32M | 24.03 | 2.11% | Share |
| 15 | ARWR | Arrowhead Pharm... | 18.77 | -6.1% | 2.67M | -7.99% | 34.01M | 19.28 | 1.92% | Share |
| 16 | RNA | Avidity Bioscie... | 46.07 | -0.17% | 1.11M | -1.48% | 32.79M | 45.93 | 1.85% | Share |
| 17 | WVE | Wave Life Scien... | 8.91 | +1.71% | 3.7M | -1.44% | 29.87M | 8.2 | 1.68% | Share |
| 18 | TBLA | Taboola.com Ltd... | 3.29 | -0.6% | 9.97M | 0.00% | 29.41M | 3.36 | 1.66% | Share |
| 19 | DYN | Dyne Therapeuti... | 12.51 | +2.21% | 2.72M | +101.71% | 28.43M | 22.11 | 1.60% | Share |
| 20 | SLDB | Solid Bioscienc... | 6.17 | -7.63% | 7.42M | +97.81% | 27.44M | 4.95 | 1.55% | Share |
| 21 | XENE | Xenon Pharmaceu... | 37.95 | +0.74% | 732.76K | -1.48% | 24.58M | 39.37 | 1.39% | Share |
| 22 | APGE | Apogee Therapeu... | 38.17 | +2.17% | 594.99K | -20.38% | 22.23M | 45.3 | 1.25% | Share |
| 23 | RVMD | Revolution Medi... | 36.02 | -0.14% | 563.75K | -1.36% | 19.93M | 45.35 | 1.12% | Share |
| 24 | TRVI | Trevi Therapeut... | 7.49 | -1.45% | 2.86M | -1.45% | 18.01M | 4.12 | 1.02% | Share |
| 25 | VERA | Vera Therapeuti... | 21.27 | -3.19% | 747.22K | -1.48% | 17.95M | 44.2 | 1.01% | Share |
| 26 | LXRX | Lexicon Pharmac... | 1.18 | +6.31% | 38.92M | 0.00% | 17.93M | 1.57 | 1.01% | Share |
| 27 | PRTA | Prothena Corpor... | 8.06 | +0.12% | 1.28M | +16.70% | 15.88M | 16.11 | 0.90% | Share |
| 28 | BCYC | Bicycle Therape... | 7.39 | +0.54% | 1.81M | -1.45% | 15.39M | 14 | 0.87% | Share |
| 29 | STOK | Stoke Therapeut... | 17.17 | +1.54% | 2.25M | +12.37% | 14.94M | 10.55 | 0.84% | Share |
| 30 | RYTM | Rhythm Pharmace... | 96.48 | -1.41% | 277.53K | +100.00% | 14.7M | 52.97 | 0.83% | Share |
| 31 | SMMT | Summit Therapeu... | 26.45 | -1.56% | 695K | +100.00% | 13.41M | 19.29 | 0.76% | Share |
| 32 | SEPN | Septerna, Inc. | 11.68 | -0.09% | 2.2M | 0.00% | 12.75M | 22.9 | 0.72% | Share |
| 33 | RCUS | Arcus Bioscienc... | 9.92 | -1.39% | 1.61M | 0.00% | 12.65M | 15.29 | 0.71% | Share |
| 34 | IHS | IHS Holding Lim... | 6.95 | +1.31% | 2.36M | 0.00% | 12.31M | 2.99 | 0.69% | Share |
| 35 | ERAS | Erasca, Inc. | 1.56 | -3.7% | 8.76M | -1.13% | 12M | 2.73 | 0.68% | Share |
| 36 | DNLI | Denali Therapeu... | 14.45 | -2.43% | 821.51K | -1.5% | 11.17M | 29.13 | 0.63% | Share |
| 37 | PCVX | Vaxcyte, Inc. | 31.41 | -0.44% | 295.54K | -1.48% | 11.16M | 114.27 | 0.63% | Share |
| 38 | AMZN | Amazon.com, Inc... | 230.94 | +2.84% | 56.5K | +54.79% | 10.75M | 188.75 | 0.61% | Share |
| 39 | MSFT | Microsoft Corpo... | 522.28 | +0.33% | 28.5K | +23.91% | 10.7M | 419.39 | 0.60% | Share |
| 40 | RELY | Remitly Global,... | 19.65 | -1.6% | 490.45K | 0.00% | 10.2M | 22.1 | 0.58% | Share |
| 41 | TSHA | Taysha Gene The... | 2.92 | -3.47% | 6.51M | -1.33% | 9.06M | 1.94 | 0.51% | Share |
| 42 | CGEM | Cullinan Oncolo... | 7.59 | -0.65% | 1.19M | -1.48% | 9.03M | 16.74 | 0.51% | Share |
| 43 | CRWD | CrowdStrike Hol... | 424.70 | -1.72% | 25K | +4.17% | 8.81M | 283.35 | 0.50% | Share |
| 44 | SLN | Silence Therape... | 5.63 | -3.76% | 2.79M | -1.48% | 7.87M | 18.18 | 0.44% | Share |
| 45 | GOOGL | Alphabet Inc. | 202.88 | +0.46% | 50.7K | +624.33% | 7.84M | 156.19 | 0.44% | Share |
| 46 | RNAC | Cartesian Thera... | 11.43 | -2.39% | 563.27K | -1.57% | 7.42M | 16.12 | 0.42% | Share |
| 47 | ADBE | Adobe Inc. | 348.58 | -0.71% | 19.3K | +119.35% | 7.4M | 415.2 | 0.42% | Share |
| 48 | KRRO | Korro Bio, Inc. | 19.87 | +4.97% | 418.83K | 0.00% | 7.29M | 33.42 | 0.41% | Share |
| 49 | NOW | ServiceNow, Inc... | 850.65 | -1.42% | 9.13K | +62.82% | 7.27M | 856.48 | 0.41% | Share |
| 50 | SEER | Seer, Inc. | 2.08 | -4.15% | 4M | 0.00% | 6.76M | 1.97 | 0.38% | Share |
| 51 | PDD | PDD Holdings In... | 114.74 | -1.62% | 52.9K | 0.00% | 6.26M | 125.87 | 0.35% | Share |
| 52 | SYRE | Spyre Therapeut... | 16.86 | -3.1% | 368.6K | -1.44% | 5.95M | 23.28 | 0.34% | Share |
| 53 | GOSS | Gossamer Bio, I... | 1.96 | -0.51% | 5.21M | 0.00% | 5.73M | 0.9864 | 0.32% | Share |
| 54 | ORIC | ORIC Pharmaceut... | 9.93 | +1.02% | 1.01M | 0.00% | 5.62M | 10.25 | 0.32% | Share |
| 55 | UPB | Upstream Bio, I... | 18.62 | +0.32% | 788.45K | -1.44% | 4.83M | 16.44 | 0.27% | Share |
| 56 | NVDA | NVIDIA Corporat... | 182.02 | +0.24% | 44.43K | -9.2% | 4.82M | 121.44 | 0.27% | Share |
| 57 | TSM | Taiwan Semicond... | 240.97 | -0.19% | 28.5K | +90.00% | 4.73M | 170.04 | 0.27% | Share |
| 58 | DDOG | Datadog, Inc. | 124.48 | -3.29% | 47.42K | +55.88% | 4.71M | 109.38 | 0.27% | Share |
| 59 | NMRA | Neumora Therape... | 1.58 | +1.28% | 4.36M | -0.86% | 4.36M | 12.15 | 0.25% | Share |
| 60 | FROG | JFrog Ltd. | 42.76 | +1.96% | 131.62K | +9.57% | 4.21M | 29.46 | 0.24% | Share |
| 61 | DT | Dynatrace, Inc. | 47.43 | -0.77% | 87.73K | +6.04% | 4.14M | 53.11 | 0.23% | Share |
| 62 | MTSR | Metsera, Inc. | 30.30 | -1.85% | 150K | +100.00% | 4.08M | 27.22 | 0.23% | Share |
| 63 | RCKT | Rocket Pharmace... | 3.03 | -1.94% | 591.26K | -1.46% | 3.94M | 12.57 | 0.22% | Share |
| 64 | CRM | Salesforce, Inc... | 233.32 | -1.57% | 14.6K | +100.00% | 3.92M | 268.36 | 0.22% | Share |
| 65 | EDU | New Oriental Ed... | 48.05 | +2.69% | 79.5K | +16.06% | 3.8M | 67.56 | 0.21% | Share |
| 66 | RAPP | Rapport Therape... | 14.94 | -4.23% | 378.47K | -1.49% | 3.8M | 20.48 | 0.21% | Share |
| 67 | IONQ | IonQ, Inc. | 41.00 | -0.51% | 170K | 0.00% | 3.75M | 8.74 | 0.21% | Share |
| 68 | IGMS | IGM Biosciences... | 1.27 | -2.31% | 3.26M | -2.24% | 3.74M | 16.54 | 0.21% | Share |
| 69 | AADI | Aadi Bioscience... | 2.05 | -2.38% | 2.08M | +100.00% | 3.71M | 1.78 | 0.21% | Share |
| 70 | TIL | Instil Bio, Inc... | 28.25 | +4.73% | 203.93K | +5.98% | 3.54M | 64.5 | 0.20% | Share |
| 71 | TNGX | Tango Therapeut... | 6.92 | +0.58% | 2.57M | -1.48% | 3.51M | 7.7 | 0.20% | Share |
| 72 | VIGL | Vigil Neuroscie... | 8.05 | 0.00% | 1.97M | -1.2% | 3.5M | 3.4 | 0.20% | Share |
| 73 | SION | Sionna Therapeu... | 20.91 | -0.05% | 325K | +100.00% | 3.4M | 10.46 | 0.19% | Share |
| 74 | NBIS | Nebius Group N.... | 68.46 | -3.07% | 140K | +16.67% | 2.96M | 19.25 | 0.17% | Share |
| 75 | FHTX | Foghorn Therape... | 5.14 | -0.58% | 720.72K | 0.00% | 2.63M | 9.31 | 0.15% | Share |
| 76 | RDDT | Reddit, Inc. | 243.45 | +3.70% | 23.5K | +100.00% | 2.47M | 104.9 | 0.14% | Share |
| 77 | LPLA | LPL Financial H... | 355.97 | +0.05% | 7.5K | +100.00% | 2.45M | 327.14 | 0.14% | Share |
| 78 | SGMT | Sagimet Bioscie... | 8.67 | -9.5% | 724.77K | 0.00% | 2.36M | 2.77 | 0.13% | Share |
| 79 | ELDN | Eledon Pharmace... | 2.60 | -0.19% | 690.17K | +100.00% | 2.34M | 3.39 | 0.13% | Share |
| 80 | TSLA | Tesla, Inc. | 335.58 | -1.12% | 9K | +100.00% | 2.33M | 259.16 | 0.13% | Share |
| 81 | KLRS | Kalaris Therape... | 2.30 | +0.88% | 282.59K | +100.00% | 2.27M | 8.03 | 0.13% | Share |
| 82 | MRVL | Marvell Technol... | 79.03 | -0.37% | 36.81K | +636.16% | 2.27M | 68.21 | 0.13% | Share |
| 83 | QCOM | QUALCOMM Incorp... | 158.09 | +0.96% | 14K | -6.67% | 2.15M | 170.05 | 0.12% | Share |
| 84 | BEKE | KE Holdings Inc... | 18.39 | +0.05% | 105K | +75.00% | 2.11M | 19.99 | 0.12% | Share |
| 85 | LXEO | Lexeo Therapeut... | 4.79 | +1.48% | 603.43K | 0.00% | 2.09M | 9.04 | 0.12% | Share |
| 86 | PRQR | ProQR Therapeut... | 2.02 | +0.25% | 1.55M | -1.45% | 2.06M | 2.65 | 0.12% | Share |
| 87 | PANW | Palo Alto Netwo... | 173.55 | -1.87% | 11.5K | +91.67% | 1.96M | 170.78 | 0.11% | Share |
| 88 | SAIL | SailPoint, Inc. | 19.83 | -0.35% | 95K | +100.00% | 1.78M | 18.75 | 0.10% | Share |
| 89 | BDTX | Black Diamond T... | 2.77 | +0.18% | 1.05M | 0.00% | 1.62M | 4.35 | 0.09% | Share |
| 90 | SARO | StandardAero, I... | 27.03 | -4.01% | 56.85K | +100.00% | 1.51M | 26.64 | 0.09% | Share |
| 91 | BIOA | BioAge Labs, In... | 4.47 | -1.97% | 382.41K | -1.44% | 1.44M | 17.4 | 0.08% | Share |
| 92 | TRML | Tourmaline Bio,... | 22.39 | +0.77% | 91.43K | 0.00% | 1.39M | 25.71 | 0.08% | Share |
| 93 | WK | Workiva Inc. | 72.96 | -2.51% | 17.5K | +75.00% | 1.33M | 95.1 | 0.07% | Share |
| 94 | BILL | Bill.com Holdin... | 39.46 | -2.36% | 28.5K | +100.00% | 1.31M | 45.89 | 0.07% | Share |
| 95 | PYPL | PayPal Holdings... | 69.35 | -1.81% | 20K | +33.33% | 1.3M | 74.83 | 0.07% | Share |
| 96 | GBIO | Generation Bio ... | 6.57 | -0.68% | 2.97M | -0.46% | 1.2M | 2.47 | 0.07% | Share |
| 97 | SEMR | Semrush Holding... | 7.42 | -3.32% | 125K | +257.14% | 1.17M | 10.04 | 0.07% | Share |
| 98 | PEGA | Pegasystems Inc... | 51.92 | -1.83% | 16.5K | +100.00% | 1.15M | 69.52 | 0.06% | Share |
| 99 | MDB | MongoDB, Inc. | 204.37 | -1.48% | 5.5K | +100.00% | 964.7K | 175.4 | 0.05% | Share |
| 100 | NKE | NIKE, Inc. | 76.39 | -1.04% | 15K | +100.00% | 952.2K | 63.48 | 0.05% | Share |
| 101 | INTC | Intel Corporati... | 23.86 | +7.38% | 40K | 0.00% | 908.4K | 23.46 | 0.05% | Share |
| 102 | INFA | Informatica Inc... | 24.73 | -0.02% | 50K | +100.00% | 872.5K | 17.45 | 0.05% | Share |
| 103 | BA | The Boeing Comp... | 233.18 | -0.08% | 5K | -80% | 852.75K | 177 | 0.05% | Share |
| 104 | BASE | Couchbase, Inc. | 24.34 | -0.25% | 49.85K | -16.92% | 785.14K | 15.59 | 0.04% | Share |
| 105 | AGEN | Agenus Inc. | 4.54 | -0.22% | 500K | +100.00% | 752.5K | 1.51 | 0.04% | Share |
| 106 | KRON | Kronos Bio, Inc... | 0.88 | +1.49% | 842.95K | 0.00% | 695.44K | 0.9999 | 0.04% | Share |
| 107 | PCOR | Procore Technol... | 64.64 | -1.58% | 10K | -50% | 660.2K | 61.72 | 0.04% | Share |
| 108 | RACE | Ferrari N.V. | 464.83 | +3.02% | 1.5K | -25% | 636.36K | 424.84 | 0.04% | Share |
| 109 | HOOK | HOOKIPA Pharma ... | 0.84 | -5.62% | 566.64K | 0.00% | 611.97K | 4.3 | 0.03% | Share |
| 110 | DECK | Deckers Outdoor... | 103.83 | -2.48% | 5K | +100.00% | 559.05K | 111.81 | 0.03% | Share |
| 111 | USB | U.S. Bancorp | 46.83 | +0.46% | 12.5K | +100.00% | 527.75K | 42.22 | 0.03% | Share |
| 112 | OXY | Occidental Petr... | 44.77 | +0.06% | 10K | -33.33% | 493.6K | 51.54 | 0.03% | Share |
| 113 | GDS | GDS Holdings Li... | 31.81 | -6.22% | 12.5K | +100.00% | 316.63K | 25.33 | 0.02% | Share |
| 114 | CYCN | Cyclerion Thera... | 2.34 | -5.26% | 116.16K | 0.00% | 290.39K | 2.59 | 0.02% | Share |
| 115 | IRWD | Ironwood Pharma... | 1.07 | -1.38% | 110.53K | 0.00% | 162.48K | 4.12 | < 0.01% | Share |
| 116 | CRBU | Caribou Bioscie... | 2.00 | +2.50% | 105.35K | 0.00% | 96.19K | 1.96 | < 0.01% | Share |