ALPS Medical Breakthrough... (SBIO)
AMEX: SBIO
· Real-Time Price · USD
36.62
-0.39 (-1.05%)
At close: Sep 08, 2025, 3:59 PM
39.94
9.08%
After-hours: Sep 08, 2025, 06:59 PM EDT
SBIO Holdings List
As of Sep 9, 2025
The ALPS Medical Breakthroughs ETF is an equity ETF with a total of 101 individual holdings.
The top holdings are Axsome Therapeutics at 3.55%, Rhythm Pharmaceuticals at 3.53%, Cytokinetics, Incorporated at 3.46%, Avidity Biosciences at 3.22%, and Nuvalent at 2.95%.
101
29.31%
Equity
86.04M
n/a
0.5000%
Sector Allocation
| Rank | Symbol | Name | Price | % Change | Shares | % Weight |
|---|---|---|---|---|---|---|
| 1 | AXSM | Axsome Therapeu... | 129.29 | +3.29% | 23.38K | 3.55% |
| 2 | RYTM | Rhythm Pharmace... | 99.77 | -2.3% | 30.17K | 3.53% |
| 3 | CYTK | Cytokinetics, I... | 52.09 | -1.74% | 56.59K | 3.46% |
| 4 | RNA | Avidity Bioscie... | 48.05 | -4.59% | 57.05K | 3.22% |
| 5 | NUVL | Nuvalent, Inc. | 79.83 | -1.31% | 31.49K | 2.95% |
| 6 | MRUS | Merus N.V. | 67.19 | -0.41% | 35.3K | 2.79% |
| 7 | ALKS | Alkermes plc | 28.45 | -4.98% | 78K | 2.61% |
| 8 | PTCT | PTC Therapeutic... | 56.95 | -0.54% | 37.47K | 2.50% |
| 9 | ACAD | ACADIA Pharmace... | 25.39 | +0.51% | 79.19K | 2.36% |
| 10 | KRYS | Krystal Biotech... | 145.20 | -3.37% | 13.71K | 2.34% |
| 11 | PCVX | Vaxcyte, Inc. | 32.41 | -1.85% | 61.09K | 2.33% |
| 12 | ACLX | Arcellx, Inc. | 71.11 | -2.08% | 26.12K | 2.18% |
| 13 | MLTX | MoonLake Immuno... | 61.12 | +2.83% | 30.09K | 2.16% |
| 14 | MIRM | Mirum Pharmaceu... | 77.39 | +1.75% | 23.46K | 2.13% |
| 15 | ARWR | Arrowhead Pharm... | 27.17 | -6.55% | 65.36K | 2.08% |
| 16 | MTSR | Metsera, Inc. | 35.10 | -2.15% | 49.72K | 2.05% |
| 17 | AKRO | Akero Therapeut... | 44.57 | -0.34% | 37.75K | 1.98% |
| 18 | ZLAB | Zai Lab Limited | 31.33 | +1.85% | 53.35K | 1.96% |
| 19 | PTGX | Protagonist The... | 56.19 | -7.17% | 29.41K | 1.94% |
| 20 | APLS | Apellis Pharmac... | 26.91 | -4.34% | 59.45K | 1.88% |
| 21 | CRNX | Crinetics Pharm... | 35.14 | -1.32% | 44.32K | 1.83% |
| 22 | XENE | Xenon Pharmaceu... | 38.19 | -2.6% | 36.31K | 1.63% |
| 23 | VKTX | Viking Therapeu... | 25.48 | -5.56% | 53.21K | 1.59% |
| 24 | NAMS | NewAmsterdam Ph... | 25.09 | -7.07% | 53.13K | 1.56% |
| 25 | CGON | CG Oncology, In... | 33.69 | +1.87% | 36.02K | 1.43% |
| 26 | FOLD | Amicus Therapeu... | 7.98 | -0.13% | 145.71K | 1.36% |
| 27 | TARS | Tarsus Pharmace... | 56.89 | -1.28% | 19.9K | 1.33% |
| 28 | CELC | Celcuity Inc. | 62.53 | +12.29% | 17.98K | 1.32% |
| 29 | DNLI | Denali Therapeu... | 15.50 | +0.45% | 68.75K | 1.25% |
| 30 | GLPG | Galapagos N.V. | 33.55 | +0.57% | 31.04K | 1.22% |
| 31 | IRON | Disc Medicine, ... | 61.91 | +1.89% | 16.44K | 1.20% |
| 32 | AGIO | Agios Pharmaceu... | 36.41 | +1.11% | 27.44K | 1.17% |
| 33 | IDYA | IDEAYA Bioscien... | 23.39 | -13.88% | 41.45K | 1.14% |
| 34 | TVTX | Travere Therape... | 21.20 | -2.03% | 42.07K | 1.05% |
| 35 | IMCR | Immunocore Hold... | 36.64 | -1.51% | 23.75K | 1.02% |
| 36 | APGE | Apogee Therapeu... | 38.42 | +1.45% | 21.81K | 0.98% |
| 37 | BCRX | BioCryst Pharma... | 8.19 | -0.97% | 98.99K | 0.95% |
| 38 | MNKD | MannKind Corpor... | 5.57 | +0.54% | 143.86K | 0.94% |
| 39 | VCEL | Vericel Corpora... | 33.22 | -2.44% | 23.82K | 0.93% |
| 40 | AUPH | Aurinia Pharmac... | 12.30 | -0.81% | 63.93K | 0.92% |
| 41 | VRDN | Viridian Therap... | 19.81 | +5.82% | 38.57K | 0.90% |
| 42 | VERA | Vera Therapeuti... | 24.75 | +2.32% | 30.23K | 0.88% |
| 43 | EWTX | Edgewise Therap... | 14.88 | -4.43% | 49.84K | 0.87% |
| 44 | CLDX | Celldex Therape... | 23.40 | +2.32% | 31.42K | 0.86% |
| 45 | NVAX | Novavax, Inc. | 7.73 | -2.15% | 76.62K | 0.69% |
| 46 | RCUS | Arcus Bioscienc... | 11.44 | -6.19% | 50.08K | 0.67% |
| 47 | GPCR | Structure Thera... | 20.86 | -5.53% | 27.26K | 0.67% |
| 48 | STOK | Stoke Therapeut... | 21.99 | +6.33% | 25.82K | 0.67% |
| 49 | PHVS | Pharvaris N.V. | 21.83 | -5.29% | 25.8K | 0.66% |
| 50 | NUVB | Nuvation Bio In... | 3.48 | -10.64% | 160.6K | 0.66% |
| 51 | RAPP | Rapport Therape... | 31.47 | +119.15% | 17.29K | 0.64% |
| 52 | SPRY | ARS Pharmaceuti... | 10.70 | +6.26% | 46.5K | 0.58% |
| 53 | DNTH | Dianthus Therap... | 31.80 | +20.00% | 15.23K | 0.57% |
| 54 | UPB | Upstream Bio, I... | 18.73 | -6.21% | 25.41K | 0.56% |
| 55 | URGN | UroGen Pharma L... | 21.42 | +13.45% | 21.78K | 0.55% |
| 56 | TRVI | Trevi Therapeut... | 7.59 | +8.27% | 56.42K | 0.50% |
| 57 | ZBIO | Zenas BioPharma... | 21.52 | +4.90% | 19.78K | 0.50% |
| 58 | GERN | Geron Corporati... | 1.37 | -2.14% | 301.44K | 0.48% |
| 59 | PRAX | Praxis Precisio... | 40.75 | -13.02% | 9.64K | 0.46% |
| 60 | AKBA | Akebia Therapeu... | 3.13 | +5.74% | 124.3K | 0.46% |
| 61 | IMNM | Immunome, Inc. | 9.40 | -10.65% | 41.18K | 0.45% |
| 62 | AVXL | Anavex Life Sci... | 9.35 | -0.53% | 40.44K | 0.44% |
| 63 | TRML | Tourmaline Bio,... | 30.18 | +12.86% | 12.14K | 0.43% |
| 64 | DAWN | Day One Biophar... | 7.47 | -1.06% | 48K | 0.42% |
| 65 | RIGL | Rigel Pharmaceu... | 40.87 | -1.14% | 8.51K | 0.41% |
| 66 | VIR | Vir Biotechnolo... | 5.19 | -1.52% | 65.41K | 0.40% |
| 67 | IMTX | Immatics N.V. | 5.81 | -7.19% | 57.55K | 0.39% |
| 68 | KURA | Kura Oncology, ... | 8.14 | -0.97% | 40.94K | 0.39% |
| 69 | TBPH | Theravance Biop... | 13.92 | -0.22% | 23.7K | 0.39% |
| 70 | RLAY | Relay Therapeut... | 4.06 | -1.46% | 81.19K | 0.39% |
| 71 | RZLT | Rezolute, Inc. | 7.95 | -0.62% | 40.45K | 0.38% |
| 72 | FLGT | Fulgent Genetic... | 22.27 | +1.46% | 14.4K | 0.38% |
| 73 | BCAX | Bicara Therapeu... | 12.29 | +1.91% | 25.82K | 0.37% |
| 74 | MAZE | Maze Therapeuti... | 14.97 | -5.73% | 20.68K | 0.36% |
| 75 | ANAB | AnaptysBio, Inc... | 22.19 | +1.32% | 13.93K | 0.36% |
| 76 | TYRA | Tyra Bioscience... | 12.13 | -4.11% | 25.21K | 0.36% |
| 77 | TERN | Terns Pharmaceu... | 7.28 | +0.83% | 41.38K | 0.35% |
| 78 | KROS | Keros Therapeut... | 15.47 | -0.77% | 19.26K | 0.35% |
| 79 | PVLA | Palvella Therap... | 55.02 | -1.19% | 5.22K | 0.34% |
| 80 | GOSS | Gossamer Bio, I... | 2.66 | -9.52% | 107.62K | 0.34% |
| 81 | XNCR | Xencor, Inc. | 8.41 | -1.64% | 33.69K | 0.33% |
| 82 | OLMA | Olema Pharmaceu... | 7.58 | -8.78% | 32.39K | 0.29% |
| 83 | ARCT | Arcturus Therap... | 17.84 | -0.06% | 12.82K | 0.27% |
| 84 | RGNX | REGENXBIO Inc. | 9.48 | -2.37% | 23.73K | 0.26% |
| 85 | CMPX | Compass Therape... | 3.44 | +0.15% | 65.46K | 0.26% |
| 86 | CMPS | COMPASS Pathway... | 4.98 | -3.11% | 44.24K | 0.26% |
| 87 | REPL | Replimune Group... | 6.04 | -4.58% | 36.51K | 0.26% |
| 88 | PRTA | Prothena Corpor... | 8.49 | -0.7% | 25.47K | 0.25% |
| 89 | ERAS | Erasca, Inc. | 1.55 | -3.73% | 134.09K | 0.24% |
| 90 | ATXS | Astria Therapeu... | 7.43 | -1.2% | 26.69K | 0.23% |
| 91 | DCTH | Delcath Systems... | 11.55 | -0.86% | 16.52K | 0.22% |
| 92 | YMAB | Y-mAbs Therapeu... | 8.59 | +0.12% | 21.44K | 0.22% |
| 93 | AUTL | Autolus Therape... | 1.43 | -2.05% | 126.01K | 0.21% |
| 94 | MBX | MBX Biosciences... | 10.90 | -5.63% | 15.84K | 0.20% |
| 95 | BCYC | Bicycle Therape... | 7.00 | -2.23% | 22.6K | 0.19% |
| 96 | CAPR | Capricor Therap... | 6.35 | -5.79% | 21.64K | 0.16% |
| 97 | AVIR | Atea Pharmaceut... | 3.25 | -3.56% | 40.51K | 0.15% |
| 98 | VNDA | Vanda Pharmaceu... | 4.55 | -1.3% | 27.86K | 0.15% |
| 99 | CADL | Candel Therapeu... | 5.10 | +2.00% | 23.73K | 0.14% |
| 100 | ANNX | Annexon, Inc. | 2.21 | +1.84% | 51.95K | 0.14% |
| 101 | TNXP | Tonix Pharmaceu... | 25.29 | -4.71% | 3.48K | 0.10% |