Price Alert

ALPS Medical Breakthrough... (SBIO)

AMEX: SBIO · Real-Time Price · USD

34.85

-0.20 (-0.56%)

At close: Aug 18, 2025, 3:59 PM

35.26

1.18%

After-hours: Aug 18, 2025, 07:45 PM EDT

SBIO Holdings List

As of Aug 12, 2025

The ALPS Medical Breakthroughs ETF is an equity ETF with a total of 103 individual holdings. The top holdings are Rhythm Pharmaceuticals at 3.71%, Avidity Biosciences at 3.43%, Axsome Therapeutics at 3.17%, Nuvalent at 3.08%, and Merus at 2.98%.

Total Holdings

103

Top 10 Percentage

29.25%

Asset Class

Equity

Assets

77.06M

PE Ratio

n/a

Expense Ratio

0.5000%

Sector Allocation

Rank	Symbol	Name	Price	% Change	Shares	% Weight
1	RYTM	Rhythm Pharmace...	98.06	+0.46%	30.29K	3.71%
2	RNA	Avidity Bioscie...	44.47	-4.3%	57.67K	3.43%
3	AXSM	Axsome Therapeu...	111.07	+1.70%	23.53K	3.17%
4	NUVL	Nuvalent, Inc.	75.03	-1.33%	31.73K	3.08%
5	MRUS	Merus N.V.	66.05	-1.79%	35.58K	2.98%
6	ALKS	Alkermes plc	28.15	-3.1%	78.84K	2.71%
7	VKTX	Viking Therapeu...	42.18	+5.37%	53.78K	2.67%
8	ACAD	ACADIA Pharmace...	25.05	-1.11%	80.04K	2.58%
9	CYTK	Cytokinetics, I...	38.95	+0.74%	57.1K	2.46%
10	KRYS	Krystal Biotech...	146.32	-2.63%	13.75K	2.46%
11	ZLAB	Zai Lab Limited	35.67	-0.17%	53.92K	2.42%
12	AKRO	Akero Therapeut...	48.69	-1.4%	38.06K	2.38%
13	PCVX	Vaxcyte, Inc.	32.08	-1.9%	61.74K	2.38%
14	ACLX	Arcellx, Inc.	71.60	-3.35%	26.3K	2.36%
15	PTCT	PTC Therapeutic...	49.77	+1.95%	37.87K	2.13%
16	MLTX	MoonLake Immuno...	53.70	-1.27%	30.41K	2.11%
17	PTGX	Protagonist The...	56.13	+0.11%	29.58K	2.06%
18	MIRM	Mirum Pharmaceu...	66.68	-1.84%	23.61K	2.02%
19	MTSR	Metsera, Inc.	32.47	+4.27%	50.26K	1.97%
20	APLS	Apellis Pharmac...	27.36	-1.41%	60.09K	1.86%
21	NAMS	NewAmsterdam Ph...	25.41	+1.36%	53.7K	1.70%
22	XENE	Xenon Pharmaceu...	37.83	-1.05%	36.7K	1.62%
23	CRNX	Crinetics Pharm...	29.72	-3.26%	44.8K	1.59%
24	ARWR	Arrowhead Pharm...	19.91	-2.93%	66.06K	1.48%
25	TARS	Tarsus Pharmace...	54.57	+0.66%	20.11K	1.31%
26	GLPG	Galapagos N.V.	32.88	+1.26%	31.37K	1.28%
27	FOLD	Amicus Therapeu...	7.42	+0.27%	147.27K	1.27%
28	AGIO	Agios Pharmaceu...	37.45	+1.19%	27.73K	1.26%
29	DNLI	Denali Therapeu...	14.82	+0.85%	69.49K	1.25%
30	IRON	Disc Medicine, ...	58.85	-1.69%	16.51K	1.25%
31	IDYA	IDEAYA Bioscien...	24.73	+1.66%	41.89K	1.24%
32	CGON	CG Oncology, In...	26.15	+1.75%	36.41K	1.13%
33	VCEL	Vericel Corpora...	36.29	+0.03%	24.07K	1.11%
34	CELC	Celcuity Inc.	51.55	-0.46%	18.07K	1.09%
35	BCRX	BioCryst Pharma...	8.38	+0.18%	100.06K	1.06%
36	SPRY	ARS Pharmaceuti...	14.03	-3.44%	47K	1.00%
37	IMCR	Immunocore Hold...	32.35	-1.61%	24K	0.99%
38	APGE	Apogee Therapeu...	36.93	-0.97%	22.04K	0.99%
39	AUPH	Aurinia Pharmac...	12.21	-0.45%	64.62K	0.96%
40	TVTX	Travere Therape...	18.78	-0.21%	42.52K	0.95%
41	VRDN	Viridian Therap...	18.10	-2.37%	38.99K	0.85%
42	EWTX	Edgewise Therap...	14.00	-1.06%	50.38K	0.85%
43	CLDX	Celldex Therape...	24.47	-4.04%	31.76K	0.82%
44	NVAX	Novavax, Inc.	9.70	+1.25%	77.44K	0.81%
45	VERA	Vera Therapeuti...	21.80	+1.18%	30.55K	0.80%
46	PHVS	Pharvaris N.V.	22.09	-0.94%	26.07K	0.70%
47	MNKD	MannKind Corpor...	3.81	+2.28%	145.4K	0.65%
48	GPCR	Structure Thera...	19.95	-0.84%	27.56K	0.63%
49	AVXL	Anavex Life Sci...	9.58	-3.67%	40.87K	0.60%
50	RCUS	Arcus Bioscienc...	10.46	+0.67%	50.62K	0.60%
51	PRAX	Praxis Precisio...	46.61	-1%	9.75K	0.57%
52	UPB	Upstream Bio, I...	18.01	-4.86%	25.69K	0.55%
53	AKBA	Akebia Therapeu...	3.12	-4.15%	125.63K	0.55%
54	TRVI	Trevi Therapeut...	7.46	-0.86%	57.02K	0.54%
55	GERN	Geron Corporati...	1.45	-0.34%	304.68K	0.54%
56	IMNM	Immunome, Inc.	10.26	-0.24%	41.62K	0.52%
57	URGN	UroGen Pharma L...	19.42	-1.47%	22.02K	0.52%
58	IMTX	Immatics N.V.	6.20	-2.05%	58.17K	0.48%
59	NUVB	Nuvation Bio In...	2.89	+5.09%	162.32K	0.47%
60	STOK	Stoke Therapeut...	18.52	+1.73%	26.09K	0.45%
61	AUTL	Autolus Therape...	1.88	+5.34%	127.37K	0.41%
62	FLGT	Fulgent Genetic...	21.50	+1.13%	14.55K	0.39%
63	ZBIO	Zenas BioPharma...	17.18	+2.14%	20K	0.39%
64	DNTH	Dianthus Therap...	21.00	+1.23%	15.4K	0.38%
65	RIGL	Rigel Pharmaceu...	40.08	+1.43%	8.6K	0.37%
66	DAWN	Day One Biophar...	6.82	+1.04%	48.52K	0.37%
67	VIR	Vir Biotechnolo...	4.47	-1%	66.11K	0.37%
68	ANAB	AnaptysBio, Inc...	20.03	-0.55%	14.07K	0.36%
69	MAZE	Maze Therapeuti...	13.30	-1.48%	20.9K	0.36%
70	TBPH	Theravance Biop...	13.60	+3.38%	23.96K	0.35%
71	RLAY	Relay Therapeut...	3.48	-1.55%	82.06K	0.35%
72	TERN	Terns Pharmaceu...	6.76	-4.04%	41.83K	0.34%
73	BCAX	Bicara Therapeu...	11.46	-1.55%	26.1K	0.34%
74	KROS	Keros Therapeut...	14.53	+0.35%	19.46K	0.34%
75	TYRA	Tyra Bioscience...	10.82	+0.84%	25.48K	0.33%
76	TRML	Tourmaline Bio,...	22.16	-1.79%	12.27K	0.33%
77	RAPP	Rapport Therape...	14.58	-0.85%	17.48K	0.32%
78	RZLT	Rezolute, Inc.	6.55	+0.85%	40.88K	0.32%
79	XNCR	Xencor, Inc.	7.81	+1.69%	34.05K	0.31%
80	KURA	Kura Oncology, ...	7.48	+1.91%	41.38K	0.30%
81	CMPX	Compass Therape...	2.88	-3.2%	66.16K	0.29%
82	PVLA	Palvella Therap...	49.76	+5.19%	5.27K	0.28%
83	ERAS	Erasca, Inc.	1.53	-6.4%	135.53K	0.26%
84	PRTA	Prothena Corpor...	8.54	+3.50%	25.74K	0.26%
85	CMPS	COMPASS Pathway...	4.25	-1.5%	44.72K	0.25%
86	GOSS	Gossamer Bio, I...	2.00	+1.79%	108.77K	0.24%
87	ITOS	iTeos Therapeut...	10.11	-0.05%	18.31K	0.24%
88	YMAB	Y-mAbs Therapeu...	8.53	+0.12%	21.67K	0.24%
89	REPL	Replimune Group...	5.32	-4.32%	36.9K	0.24%
90	ATXS	Astria Therapeu...	6.77	-1.17%	26.98K	0.23%
91	MBX	MBX Biosciences...	14.66	-0.37%	16.01K	0.23%
92	RGNX	REGENXBIO Inc.	8.72	-1.08%	23.98K	0.23%
93	DCTH	Delcath Systems...	10.63	+2.65%	16.7K	0.23%
94	CAPR	Capricor Therap...	7.71	-3.08%	21.88K	0.22%
95	BCYC	Bicycle Therape...	7.54	+1.28%	22.84K	0.22%
96	TNXP	Tonix Pharmaceu...	40.04	-22.03%	3.52K	0.20%
97	OLMA	Olema Pharmaceu...	5.76	+4.63%	32.73K	0.19%
98	CADL	Candel Therapeu...	5.96	-2.05%	23.98K	0.19%
99	ARCT	Arcturus Therap...	17.93	-7.96%	12.96K	0.19%
100	AVIR	Atea Pharmaceut...	3.53	+0.86%	40.95K	0.19%
101	ANNX	Annexon, Inc.	2.34	-4.29%	52.51K	0.16%
102	VNDA	Vanda Pharmaceu...	4.56	+4.63%	28.16K	0.15%
103		Cash and equiva...	n/a	n/a	12.61K	0.02%