Spyre Therapeutics Inc.

11.73
-0.66 (-5.33%)
At close: Apr 08, 2025, 3:59 PM
11.99
2.24%
After-hours: Apr 08, 2025, 07:00 PM EDT

Company Description

Spyre Therapeutics, Inc., a preclinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD).

It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn's disease).

The company is also developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-a4ß7) and SPY002 (anti-TL1A) antibodies, which are in preclinical studies.

In addition, its other early-stage programs include SPY003, an anti-IL-23 mAb; SPY004, a novel mechanism of action (MOA) mAb; SPY130, a combination of anti-a4ß7 and anti-IL-23 mAbs; and SPY230, a combination of anti-TL1A and anti-IL-23 mAbs.

The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023.

Spyre Therapeutics, Inc. was incorporated in 2013 and is based in Waltham, Massachusetts.

Spyre Therapeutics Inc.
Spyre Therapeutics Inc. logo
Country United States
IPO Date Apr 7, 2016
Industry Biotechnology
Sector Healthcare
Employees 65
CEO Dr. Cameron Turtle DPHIL, Ph.D.

Contact Details

Address:
221 Crescent Street
Waltham, Massachusetts
United States
Website https://www.spyre.com

Stock Details

Ticker Symbol SYRE
Exchange NASDAQ
Fiscal Year January - December
Reporting Currency USD
CIK Code 0001636282
CUSIP Number 00773J202
ISIN Number US00773J2024
Employer ID 46-4312787
SIC Code 2834

Key Executives

Name Position
Dr. Cameron Turtle DPHIL, Ph.D. Chief Executive Officer & Director
Heidy Abreu King-Jones J.D., L.L.M. Chief Legal Officer & Corporate Secretary
Scott L. Burrows Chief Financial Officer
Brian Connolly Chief Technical Officer
Dr. Janet Gunzner-Toste M.B.A., Ph.D. Senior Vice President of Operations
Dr. Justin LaFountaine Ph.D. Senior Vice President of Corporate Development
Dr. Sheldon Sloan M.B.E., M.D. Chief Medical Officer
Eric McIntyre Vice President of Finance & Investor Relations
James Myers Vice President of Quality & Compliance
Melissa Cooper Senior Vice President of People

Latest SEC Filings

Date Type Title
Mar 07, 2025 POS AM Filing
Mar 06, 2025 8-K Current Report
Feb 27, 2025 S-3 Filing
Feb 27, 2025 S-8 Filing
Feb 27, 2025 8-K Current Report
Feb 27, 2025 10-K Annual Report
Feb 14, 2025 SCHEDULE 13G/A [Amend] Filing
Feb 14, 2025 SCHEDULE 13G/A [Amend] Filing
Feb 14, 2025 SCHEDULE 13G/A [Amend] Filing
Jan 17, 2025 4 Filing