SPDR S&P Biotech ETF (XBI)
AMEX: XBI
· Real-Time Price · USD
101.39
1.19 (1.19%)
At close: Oct 01, 2025, 3:59 PM
101.37
-0.02%
After-hours: Oct 01, 2025, 05:51 PM EDT
XBI Holdings List
As of Sep 30, 2025
The SPDR S&P Biotech ETF is an equity ETF with a total of 128 individual holdings.
The top holdings are CRISPR Therapeutics at 2.20%, United Therapeutics at 2.03%, AbbVie at 1.94%, Exelixis at 1.93%, and Regeneron Pharmaceuticals at 1.89%.
128
19.28%
Equity
5.53B
n/a
0.3500%
Sector Allocation
| Rank | Symbol | Name | Price | % Change | Shares | % Weight |
|---|---|---|---|---|---|---|
| 1 | CRSP | CRISPR Therapeu... | 66.16 | +2.08% | 1.94M | 2.20% |
| 2 | UTHR | United Therapeu... | 438.18 | +4.53% | 255.93K | 2.03% |
| 3 | ABBV | AbbVie Inc. | 244.39 | +5.55% | 479.35K | 1.94% |
| 4 | EXEL | Exelixis, Inc. | 41.20 | -0.24% | 2.69M | 1.93% |
| 5 | REGN | Regeneron Pharm... | 599.94 | +6.70% | 182.58K | 1.89% |
| 6 | MRNA | Moderna, Inc. | 27.60 | +6.85% | 4.17M | 1.87% |
| 7 | NBIX | Neurocrine Bios... | 137.00 | -2.41% | 718.37K | 1.87% |
| 8 | IONS | Ionis Pharmaceu... | 65.80 | +0.58% | 1.59M | 1.86% |
| 9 | VRTX | Vertex Pharmace... | 404.09 | +3.18% | 261.23K | 1.85% |
| 10 | BMRN | BioMarin Pharma... | 54.86 | +1.29% | 1.86M | 1.84% |
| 11 | MDGL | Madrigal Pharma... | 449.14 | -2.08% | 235.93K | 1.83% |
| 12 | RVMD | Revolution Medi... | 45.86 | -1.8% | 2.27M | 1.82% |
| 13 | AMGN | Amgen Inc. | 298.50 | +5.78% | 364.32K | 1.82% |
| 14 | EXAS | Exact Sciences ... | 56.43 | +3.14% | 1.85M | 1.82% |
| 15 | HALO | Halozyme Therap... | 74.94 | +2.18% | 1.34M | 1.81% |
| 16 | GILD | Gilead Sciences... | 111.15 | +0.14% | 880.45K | 1.81% |
| 17 | BIIB | Biogen Inc. | 154.22 | +10.09% | 711.51K | 1.79% |
| 18 | NTRA | Natera, Inc. | 161.61 | +0.40% | 597.58K | 1.78% |
| 19 | INCY | Incyte Corporat... | 86.70 | +2.23% | 1.18M | 1.78% |
| 20 | ALNY | Alnylam Pharmac... | 460.65 | +1.02% | 216.19K | 1.77% |
Page 1 of 7