SPDR S&P Biotech ETF (XBI)
80.24
-0.65 (-0.80%)
At close: Apr 25, 2025, 3:59 PM
80.25
0.01%
After-hours: Apr 25, 2025, 05:45 PM EDT
XBI Holdings List
As of Apr 23, 2025
The SPDR S&P Biotech ETF holds 127 different assets
and the largest one in the portfolio is Natera, Inc., making up 2.70% of
the total.
| Rank | Symbol | Name | Price | % Change | Shares | % Weight |
|---|---|---|---|---|---|---|
| 1 | NTRA | Natera, Inc. | 153.71 | -0.5% | 901.43K | 2.70% |
| 2 | VRTX | Vertex Pharmace... | 493.96 | +0.30% | 262.91K | 2.67% |
| 3 | ALNY | Alnylam Pharmac... | 251.72 | +3.75% | 537.32K | 2.64% |
| 4 | INSM | Insmed Incorpor... | 69.76 | +1.16% | 1.76M | 2.60% |
| 5 | UTHR | United Therapeu... | 291.65 | -1.61% | 424.21K | 2.58% |
| 6 | EXAS | Exact Sciences ... | 45.52 | -0.19% | 2.81M | 2.57% |
| 7 | NBIX | Neurocrine Bios... | 106.69 | +0.87% | 1.19M | 2.52% |
| 8 | GILD | Gilead Sciences... | 103.19 | -2.79% | 1.14M | 2.50% |
| 9 | AMGN | Amgen Inc. | 280.72 | +0.31% | 416.85K | 2.41% |
| 10 | REGN | Regeneron Pharm... | 602.46 | +0.45% | 188.92K | 2.29% |
| 11 | BIIB | Biogen Inc. | 118.87 | -0.54% | 929.19K | 2.29% |
| 12 | INCY | Incyte Corporat... | 59.19 | +0.36% | 1.92M | 2.29% |
| 13 | MDGL | Madrigal Pharma... | 326.66 | +2.10% | 360.4K | 2.26% |
| 14 | ABBV | AbbVie Inc. | 186.34 | +3.31% | 614.21K | 2.21% |
| 15 | EXEL | Exelixis, Inc. | 37.42 | +0.56% | 2.77M | 2.10% |
| 16 | BPMC | Blueprint Medic... | 87.58 | +1.73% | 1.2M | 2.07% |
| 17 | BMRN | BioMarin Pharma... | 63.26 | +0.83% | 1.58M | 2.01% |
| 18 | MRNA | Moderna, Inc. | 27.19 | -0.73% | 3.72M | 1.99% |
| 19 | BBIO | BridgeBio Pharm... | 36.28 | +0.89% | 2.44M | 1.73% |
| 20 | TGTX | TG Therapeutics... | 41.35 | +2.62% | 2.19M | 1.73% |
| 21 | HALO | Halozyme Therap... | 60.47 | +2.06% | 1.34M | 1.62% |
| 22 | SMMT | Summit Therapeu... | 23.36 | -36.35% | 2.77M | 1.57% |
| 23 | RVMD | Revolution Medi... | 38.82 | +0.62% | 1.97M | 1.51% |
| 24 | SRPT | Sarepta Therape... | 60.46 | -2.1% | 1.17M | 1.45% |
| 25 | CRSP | CRISPR Therapeu... | 38.31 | -2.05% | 1.76M | 1.43% |
| 26 | CYTK | Cytokinetics, I... | 40.44 | +0.27% | 1.78M | 1.39% |
| 27 | ROIV | Roivant Science... | 11.05 | +0.45% | 5.97M | 1.29% |
| 28 | IONS | Ionis Pharmaceu... | 29.66 | +0.32% | 2.12M | 1.28% |
| 29 | ADMA | ADMA Biologics,... | 21.86 | -2.1% | 2.69M | 1.19% |
| 30 | VKTX | Viking Therapeu... | 25.04 | -2.42% | 2.21M | 1.17% |
| 31 | SWTX | SpringWorks The... | 44.73 | -0.46% | 1.34M | 1.12% |
| 32 | RNA | Avidity Bioscie... | 30.79 | -0.45% | 1.75M | 1.07% |
| 33 | PCVX | Vaxcyte, Inc. | 32.81 | -4.93% | 1.59M | 1.03% |
| 34 | ALKS | Alkermes plc | 27.83 | +0.58% | 1.81M | 1.02% |
| 35 | KRYS | Krystal Biotech... | 168.40 | -0.43% | 291.25K | 1.02% |
| 36 | ACLX | Arcellx, Inc. | 63.79 | -0.28% | 705.08K | 0.92% |
| 37 | TWST | Twist Bioscienc... | 40.16 | -0.01% | 1.2M | 0.92% |
| 38 | NUVL | Nuvalent, Inc. | 73.32 | -0.89% | 616.95K | 0.91% |
| 39 | SRRK | Scholar Rock Ho... | 32.79 | -4.62% | 1.35M | 0.88% |
| 40 | VCYT | Veracyte, Inc. | 32.23 | +0.28% | 1.34M | 0.86% |
| 41 | RYTM | Rhythm Pharmace... | 63.86 | +1.41% | 695.76K | 0.85% |
| 42 | RXRX | Recursion Pharm... | 5.72 | -0.43% | 7.21M | 0.84% |
| 43 | SLNO | Soleno Therapeu... | 73.32 | -1.23% | 558.66K | 0.83% |
| 44 | CRNX | Crinetics Pharm... | 32.42 | -2.91% | 1.23M | 0.80% |
| 45 | RARE | Ultragenyx Phar... | 38.05 | +1.09% | 1.07M | 0.80% |
| 46 | APLS | Apellis Pharmac... | 17.45 | -0.51% | 2.17M | 0.78% |
| 47 | ACAD | ACADIA Pharmace... | 14.75 | -0.54% | 2.41M | 0.72% |
| 48 | AKRO | Akero Therapeut... | 41.05 | +0.15% | 892.75K | 0.71% |
| 49 | PTCT | PTC Therapeutic... | 49.65 | +0.20% | 687.77K | 0.69% |
| 50 | AGIO | Agios Pharmaceu... | 29.51 | +0.85% | 1.13M | 0.66% |
| 51 | BHVN | Biohaven Ltd. | 19.80 | -15.38% | 1.44M | 0.63% |
| 52 | ARWR | Arrowhead Pharm... | 13.23 | -0.79% | 2.32M | 0.60% |
| 53 | CPRX | Catalyst Pharma... | 23.43 | +1.03% | 1.26M | 0.59% |
| 54 | TVTX | Travere Therape... | 18.33 | +3.98% | 1.75M | 0.58% |
| 55 | BEAM | Beam Therapeuti... | 19.54 | -3.12% | 1.44M | 0.57% |
| 56 | IDYA | IDEAYA Bioscien... | 19.00 | -0.37% | 1.46M | 0.56% |
| 57 | ARQT | Arcutis Biother... | 14.61 | -0.78% | 1.93M | 0.55% |
| 58 | SNDX | Syndax Pharmace... | 13.34 | +0.26% | 2.07M | 0.55% |
| 59 | CLDX | Celldex Therape... | 19.56 | -0.1% | 1.31M | 0.53% |
| 60 | MIRM | Mirum Pharmaceu... | 40.82 | +0.86% | 624.96K | 0.51% |
| 61 | PTGX | Protagonist The... | 44.48 | -0.82% | 533.36K | 0.51% |
| 62 | BCRX | BioCryst Pharma... | 8.39 | +2.13% | 3.05M | 0.49% |
| 63 | IMVT | Immunovant, Inc... | 14.67 | -2.65% | 1.67M | 0.49% |
| 64 | ARDX | Ardelyx, Inc. | 5.26 | +4.88% | 4.74M | 0.47% |
| 65 | DNLI | Denali Therapeu... | 15.69 | +1.26% | 1.56M | 0.47% |
| 66 | VCEL | Vericel Corpora... | 39.74 | -3.29% | 574.79K | 0.47% |
| 67 | VERA | Vera Therapeuti... | 23.26 | -0.89% | 1.02M | 0.45% |
| 68 | GRAL | GRAIL, Inc. | 37.23 | -1.22% | 733.83K | 0.45% |
| 69 | CDNA | CareDx, Inc | 18.51 | +0.11% | 1.2M | 0.44% |
| 70 | DVAX | Dynavax Technol... | 10.82 | -0.73% | 1.98M | 0.44% |
| 71 | FOLD | Amicus Therapeu... | 7.36 | +2.15% | 3.06M | 0.44% |
| 72 | NVAX | Novavax, Inc. | 6.63 | -6.15% | 3.35M | 0.43% |
| 73 | KYMR | Kymera Therapeu... | 33.26 | -0.91% | 710.8K | 0.42% |
| 74 | JANX | Janux Therapeut... | 31.06 | -3.15% | 678.21K | 0.42% |
| 75 | APGE | Apogee Therapeu... | 36.87 | -0.49% | 518.19K | 0.38% |
| 76 | IRON | Disc Medicine, ... | 45.34 | -1.8% | 410.29K | 0.38% |
| 77 | NTLA | Intellia Therap... | 8.29 | +1.41% | 2.17M | 0.37% |
| 78 | CGON | CG Oncology, In... | 22.28 | +3.53% | 860.78K | 0.37% |
| 79 | DYN | Dyne Therapeuti... | 11.07 | -0.32% | 1.78M | 0.36% |
| 80 | VRDN | Viridian Therap... | 13.49 | -0.48% | 1.28M | 0.36% |
| 81 | IOVA | Iovance Biother... | 3.50 | +4.32% | 5.08M | 0.34% |
| 82 | NRIX | Nurix Therapeut... | 11.57 | +0.43% | 1.33M | 0.32% |
| 83 | GERN | Geron Corporati... | 1.42 | -0.35% | 10.62M | 0.31% |
| 84 | MNKD | MannKind Corpor... | 4.74 | +1.39% | 3.18M | 0.30% |
| 85 | QURE | uniQure N.V. | 14.15 | -0.74% | 995.17K | 0.30% |
| 86 | AVXL | Anavex Life Sci... | 9.40 | -0.53% | 1.54M | 0.29% |
| 87 | CAPR | Capricor Therap... | 13.00 | -2.11% | 1M | 0.29% |
| 88 | SPRY | ARS Pharmaceuti... | 13.78 | -5.87% | 907.77K | 0.28% |
| 89 | MYGN | Myriad Genetics... | 7.42 | +0.61% | 1.77M | 0.27% |
| 90 | RCKT | Rocket Pharmace... | 7.24 | -2.62% | 1.88M | 0.27% |
| 91 | PRAX | Praxis Precisio... | 35.99 | -0.01% | 352.41K | 0.26% |
| 92 | VIR | Vir Biotechnolo... | 6.12 | -2.62% | 2.06M | 0.25% |
| 93 | SYRE | Spyre Therapeut... | 14.11 | -5.49% | 847.52K | 0.24% |
| 94 | XNCR | Xencor, Inc. | 10.49 | -3.18% | 1.05M | 0.23% |
| 95 | RCUS | Arcus Bioscienc... | 8.28 | -1.55% | 1.35M | 0.23% |
| 96 | ETNB | 89bio, Inc. | 6.96 | +0.87% | 1.65M | 0.23% |
| 97 | DAWN | Day One Biophar... | 7.74 | -2.03% | 1.44M | 0.22% |
| 98 | IBRX | ImmunityBio, In... | 2.60 | -3.35% | 3.91M | 0.22% |
| 99 | IMNM | Immunome, Inc. | 8.39 | -1.53% | 1.24M | 0.21% |
| 100 | KURA | Kura Oncology, ... | 6.42 | -0.08% | 1.58M | 0.21% |
| 101 | KROS | Keros Therapeut... | 14.16 | -1.8% | 666.83K | 0.19% |
| 102 | COGT | Cogent Bioscien... | 4.63 | +2.66% | 2.02M | 0.18% |
| 103 | ALT | Altimmune, Inc. | 5.08 | -1.64% | 1.73M | 0.17% |
| 104 | REPL | Replimune Group... | 9.04 | -0.22% | 947.32K | 0.17% |
| 105 | ANAB | AnaptysBio, Inc... | 20.69 | +0.39% | 375.75K | 0.17% |
| 106 | ARCT | Arcturus Therap... | 12.91 | +0.16% | 596.28K | 0.15% |
| 107 | RLAY | Relay Therapeut... | 3.20 | +0.31% | 2.47M | 0.15% |
| 108 | VERV | Verve Therapeut... | 5.76 | -0.35% | 1.36M | 0.15% |
| 109 | STOK | Stoke Therapeut... | 9.74 | -1.42% | 743.65K | 0.14% |
| 110 | EBS | Emergent BioSol... | 5.46 | +1.77% | 1.34M | 0.13% |
| 111 | DNTH | Dianthus Therap... | 21.61 | +1.79% | 287.66K | 0.13% |
| 112 | CGEM | Cullinan Oncolo... | 8.13 | -0.12% | 662.17K | 0.12% |
| 113 | AKBA | Akebia Therapeu... | 2.38 | +4.61% | 2.49M | 0.11% |
| 114 | MDXG | MiMedx Group, I... | 6.92 | +1.84% | 790.11K | 0.11% |
| 115 | PRTA | Prothena Corpor... | 9.69 | +0.36% | 530K | 0.10% |
| 116 | ORIC | ORIC Pharmaceut... | 5.11 | -1.64% | 933.1K | 0.10% |
| 117 | RIGL | Rigel Pharmaceu... | 19.30 | +1.29% | 257.83K | 0.10% |
| 118 | AVBP | ArriVent BioPha... | 20.84 | -1.54% | 209.72K | 0.09% |
| 119 | SANA | Sana Biotechnol... | 1.78 | +0.56% | 2.35M | 0.08% |
| 120 | KALV | KalVista Pharma... | 12.97 | +0.74% | 316.54K | 0.08% |
| 121 | - | Ssi us gov mone... | n/a | n/a | 3.17M | 0.07% |
| 122 | ABUS | Arbutus Biophar... | 3.29 | -1.5% | 998.66K | 0.07% |
| 123 | HUMA | Humacyte, Inc. | 1.43 | -3.38% | 2.23M | 0.06% |
| 124 | ORGO | Organogenesis H... | 4.55 | +0.44% | 385.55K | 0.04% |
| 125 | - | Contra inhibrx ... | n/a | n/a | 1.65M | 0.02% |
| 126 | - | Contra mirati t... | n/a | n/a | 1.37M | 0.02% |
| 127 | SCLX | Scilex Holding ... | 4.90 | +10.52% | 169.67K | < 0.01% |