ProQR Therapeutics N.V. (PRQR)

The total Delta Exposure (DEX) for PRQR across all expirations shows 188.98 net shares that market makers must hedge, with 195.13 from calls and 6.15 from puts. The put-call delta ratio of 0.03 shows bullish positioning with call dominance, potentially providing upward momentum but leaving the market vulnerable to sharp pullbacks. The largest delta concentration at Oct 17, 25 with 129.04 net DEX represents significant hedging pressure that may cap upside moves. The nearest expiration on Sep 19, 25 carries negative delta forcing market makers to buy shares, potentially providing support.